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Imlifidase is an IgG-inactivating therapy based on a cysteine protease originating from Streptococcus pyogenes.

It is designed to have a unique mechanism of action and a high specificity to IgG antibodies. The use of imlifidase is a novel approach to eliminate pathogenic IgG. Given its rapid onset of action, imlifidase cleaves IgG-antibodies and inhibits their activity within hours after administration.